How does Oxbryta work

Hemoglobin S is an abnormal type of hemoglobin [1]

• Responsible for red blood cells (RBCs) to become sickle shaped
• Reduces the amount of oxygen blood can carry

Oxbryta helps hemoglobin bind to oxygen [1]

• Makes it harder for RBCs to form the sickle shape
• Improves blood flow
• Increases flexibility of RBCs
  • Allows RBCs to live longer in the blood