Benefits

  • Sustained increase in hemoglobin level
  • Does not negatively affect blood viscosity (thickness)
    • May decrease frequency of pain episodes
    • May decrease the risk of stroke
  • May reduce sickling of red blood cells
    • May decrease number of hospital or emergency room admits
  • Reduced hemolysis (death of red blood cells)

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  • Safety not known for children less than 12 years of age
  • Safe dose not known for over 65 years of age
  • Risk of Oxbryta on pregnancy not known
    • Talk to your doctor before taking Oxbryta
  • Not known if it is present in breast milk
    • Talk to your doctor before you breastfeed

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  • Diarrhea
  • Nausea
  • Abdominal pain
  • Fatigue
  • Rash
  • Headache
  • Fever

(*Side effects in bold were experienced by over 10% of study participants with a difference of >5% compared to placebo)

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How does Oxbryta work?
Who should consider Oxbryta?